The JC polyoma viral coat protein VP1 was analyzed for amino acid sequences homologies to the IDSP sequence which mediates binding of VLA-4 (integrin alpha 4) to vascular cell adhesion molecule 1. Although the full sequence was not found. a DSP sequence was located near the critical arginine residue linked to infectivity of the virus and binding to sialic acid containing molecules suc... https://www.socialstudiesscholar.com/